City Language Centre (CLC) was founded by seven members in 1996. These seven members had been language trainers for the US Peace Corps and saw in CLC an opportunity to share their expertise with the wider public. Uganda is a multi-cultural and multi-lingual society, thus presenting unique challenges for both nationals and expatriates living and working here. In 1996 CLC opened on the Makerere Campus and became the first such language school in Uganda.

In 2007 CLC moved from the Makerere Campus to its own building in a suburb just south of Kampala off Entebbe Road.

From its beginnings to the present CLC has worked with both national and international clientele. Clients include: School For International Training, Concern International, German Development Service, Voluntary Services Overseas, Full Gospel Mission, Youth Alive, Lutheran World Federation, and the Missionary Sisters of Our Lady of Africa.